[on Moriarty] Irene Adler: Please don't underestimate him. He's just as brilliant as you are. And infinitely more devious. Sherlock Holmes: We'll see about that.
[Holmes is spying on Blackwood's sacrifice. A henchman tries to sneak up on him, but Watson grabs him and puts him in a hold] Dr. John Watson: I like the hat. Sherlock Holmes: Thanks, I just picked it up. Dr. John Watson: You remember your revolver? ...
Mary Morstan: It does seem a little far-fetched, though. Making all these grand assumptions based on such tiny details... Sherlock Holmes: Mm, that's not quite right, is it? In fact, the little details are by far the most important.
Lord Blackwood: Sherlock Holmes... and his loyal dog. Tell me, Doctor, as a medical man, have you enjoyed my work? Dr. John Watson: Let me show you how much I've enjoyed it... [He rushes at Blackwood, Holmes holds him back] Sherlock Holmes: Watson, d...
Sherlock Holmes: Whatever he was working on, he obviously succeeded. Dr. John Watson: How do you know? Sherlock Holmes: Otherwise, he'd still be alive.
Irene Adler: [referring to Holmes' disguise] Eye patch... nice touch.
Dr. John Watson: [Holmes is firing a gun in the house] Mrs Hudson. Mrs. Hudson: I won't go in there by myself, not while he's got a gun in his hand! Dr. John Watson: You don't have to go in there at all. Mrs. Hudson: What will I do when you leave, do...
Inspector Lestrade: And you were supposed to wait for my orders. Sherlock Holmes: If I had, you'd be cleaning up a corpse and chasing a rumor. Besides, the girl's parents hired me, not the Yard. Why they thought you'd require any assistance is beyond...
[Lestrade brings Holmes, handcuffed, before the Home Secretary, Lord Coward] Inspector Lestrade: Excuse me, my lord. I know it's unorthodox, but Mr. Holmes here has been making some serious accusations about you... [Lestrade lifts his lapel, showing ...
[about Blackwood coming back from the grave] Sherlock Holmes: Have the newspapers got wind of it yet? Constable Clark: Well, that's what we're trying to avoid, sir. Sherlock Holmes: Certainly. What's the major concern? Constable Clark: Panic. Sheer b...
Governor: Lord Henry Blackwood, you are sentenced to death for the practice of black magic, the unholy murders of five innocent young women, and the attempted murder of a sixth. Have you any final words? Lord Blackwood: Death... is only the beginning...
Sherlock Holmes: [to Lord Blackwood] I wonder if they'd let Watson and me dissect your brain. After you hang, of course. I'd wager there would be some deformity that would be scientifically significant. In that way, at least, you could serve some kin...
Palm Reader: [reading Watson's palm] I see two men. Two men. Brothers! Not in blood, but in bond.
Irene Adler: I'd say you're between jobs. Sherlock Holmes: And you, between husbands. Irene Adler: He was boring and he was jealous and he snored. I'm Irene Adler again.
Dr. John Watson: [about Irene , to Holmes] She loves an entrance, your muse.
Dr. John Watson: Holmes! Does your depravity know no bounds? Sherlock Holmes: [nonchalantly] No!
[Holmes and Watson are searching Riordan's house] Sherlock Holmes: There's one odor I can't put my finger on. Is it candy floss, molasses...? Ah! Barley sugar. [Watson turns around to see two goons enter, one holding a... ] Dr. John Watson: ...Toffee...
Mary Morstan: [Mary asks Holmes to make some deductions regarding herself] What can you tell about me? Sherlock Holmes: You? Dr. John Watson: I don't think that's... Sherlock Holmes: I don't know if that's... Dr. John Watson: Not at dinner. Sherlock ...