Sherlock Holmes: [to Watson] Never theorize before you have data. Invariably, you end up twisting facts to suit theories, instead of theories to suit facts.
Irene Adler: Why are you always so suspicious? Sherlock Holmes: Should I answer chronologically or alphabetically?
Sherlock Holmes: You have the grand gift of silence, Watson; it makes you quite invaluable as a companion. [Watson punches him in the face]
[first lines] Sherlock Holmes: [voice-over] Head cocked to the left, partial deafness in ear: first point of attack. Two: throat; paralyze vocal chords, stop scream. Three: got to be a heavy drinker, floating rib to the liver. Four: finally, drag in ...
Dr. John Watson: [Holmes points his violin bow at Watson] Get that out of my face. Sherlock Holmes: It's not in your face, it's in my hand. Dr. John Watson: Get what's in your hand out of my face.
Dr. John Watson: You've been in this room for two weeks, I insist you have to get out. Sherlock Holmes: There is absolutely nothing of interest to me, out there, on Earth, at all. Dr. John Watson: So you're free this evening? Sherlock Holmes: Absolut...
Sherlock Holmes: You've never complained about my methods before. Dr. John Watson: I'm not complaining. Sherlock Holmes: You're not? What do you call this? Dr. John Watson: I never complain! How am I complaining? When do I ever complain about you pra...
Dr. John Watson: [to Holmes, about Irene] Why is the only woman you've cared about a world class criminal? Are you a masochist?
Lord Coward: How terrible is wisdom, when it brings no profit to the wise.
Sherlock Holmes: It's a matter of professional integrity! No girl wants to marry a doctor who can't tell if a man's dead or not!
Irene Adler: I've never woke up in handcuffs before. Sherlock Holmes: I have. Naked.
Sherlock Holmes: My mind rebels at stagnation! Give me problems! Give me work!
Sherlock Holmes: There is a toxin, refined from the nectar of the rhododendron ponticum. It's quite infamous in the region of Turkey bordering the Black Sea for its ability to induce an apparently mortal paralysis. Enough to deceive even a medical mi...
Dr. John Watson: You really believe he was resurrected? Sherlock Holmes: The question is not if but how. The game's afoot. Dr. John Watson: "Follow your spirit..." Dr. John Watson, Sherlock Holmes: "And upon this charge, cry, 'God for Harry, England...
Sherlock Holmes: My journey took me some what further down the rabbit hole than I intended and though I dirtied my fluffy white tail I have emerged, enlightened.
Inspector Lestrade: You know, in another life, you'd have made an excellent criminal. Sherlock Holmes: Yes, and you, sir, an excellent policeman.
Sherlock Holmes: [after being tossed across the room] Un moment, s'il vous plait. Dredger: [affably] Je ne suis pas pressé.
Dr. John Watson: [as he's choking Dredger into unconsciousness] Relax. I'm a doctor.