When you prescribe a new drug, often you are prescribing something that has only been tested in a few thousand people for a very short period of time, perhaps only six months, and that's not long enough to know whether there are any medium- or long-t...
I knew I could never be an actor as a man. It just doesn't work, you know? And so when I was doing drag, I realized I could do that kind of stuff, and then when I was transitioning, I kind of gave up on the whole thing because I didn't think that thi...
If we lived in a time where people couldn't watch 'Lost' on Hulu or record it on their DVR, we wouldn't necessarily have succeeded. We need people to be able to catch up. Now you choose when you watch TV. We wouldn't have survived in the old days bec...
Television used to be made much more in a vacuum; the only feedback the audience had for a long time was in a Nielsen number that would arrive sometime after the show had been broadcast. And now, people are just completely engaged on so many levels, ...
When I was asked to write an article about what it was like to work with my husband on a TV show, I assumed it was because people thought it would be titillating. He's a creator/writer/producer, I'm an actress; there must be lots of gossip, in-fighti...
If you've never been on anything before, they're not going to take a risk and give you a huge job 90 percent of the time. There are exceptions to that. I certainly wasn't an exception to that. I had to pay my dues big time, but I wish somebody would ...
I remember when I first met Jason Reitman with the 'Whiplash' script; he quickly became a mentor figure who guided me through the process and also protected me and made sure that when it came time to actually make 'Whiplash,' I was able to make exact...
There is no more reason to think that they expected the world to remain static than there is to think that any of us holds a crystal ball. The only way to create a foundational document that could stand the test of time was to build in enough flexibi...
It is time... to end the long-standing and unproductive methodological debate over 'originalism' versus 'dynamism' or 'evolution' and focus instead on how, as a substantive matter, we should interpret the Constitution in the twenty-first century, and...
It might sound a small thing, but if you want to get Tom Cruise into your movie, without a track record or without those agents knowing you, it's almost impossible. Now I can get through to pretty much anyone I want. Of course, 90 per cent of the tim...
Because in order to beat Jimmy, I had to get around the ball a little bit quicker so I wasn't always on defensive and catching the ball on last stride, that I had little more time. Once I was able to get little bit quicker, then it has helped me a lo...
We're probably going to see some post-2014 military presence - some U.S. presence and a NATO presence - and while we've got much work to do in the next 29 months, we'll have additional time later for the continued professionalization of the Afghan se...
I came to NBC on 'Friday Night Lights' and they have supported that show and found ways - unprecedented ways - to keep it on the air for a long time. And when I came to them with the idea of doing 'Parenthood,' they not only supported me in doing it ...
I think no matter what you do you go through stages when you play. There was a number of times when I didn't do very well or was tired. It was too much to combine school and tennis altogether. Parents need to step in and say, take a little time off, ...
Indecision may come from an instinctive hunch that there's more you need to know - which means it's time to learn everything you can about the pros and cons of each option. You can continue on this track, however, only as long as you're unearthing ge...
Every day, I just thank the universe that I am as lucky as I am. Because, I went through periods of time when I didn't have a single bit of work. Months and months where I was auditioning all the time. I mean, all the time, and nothing was happening.
When you're doing a film, you're on a set and you have retakes and you have time to get it right. And on 'SNL' it's just go, go, go. If you can't read the cue cards or miss your mark, you're just left to sort of screw up. So there's a lot more pressu...
With 'Silver Linings,' I didn't feel - I was thinking of certain things, but I just said, 'Let me go with it.' You have to know what you're doing, where you're going with the scenes, and I put a lot of work into that. But when you're out there, at th...
With the kids around, this is a different world to me. I spend a lot of time with them till they go to their playschool. I wake up early, have breakfast with them. I come back from work and am with them again till they go to bed by 10 P.M. Touch wood...
When an audience is affected in a way that I've seen with some people, it's so inspiring to me an actor. You know that you're on the right track and you're doing work that can affect people. When that goes hand-in-hand with important issues that we'r...
In theater, you get to rehearse several weeks, you memorize everything, and by the time you open, you know what the play is. In film, it's almost the opposite. You do your work on your own and maybe have a couple of minutes to rehearse. When the came...
