While Washington pays lip service to the challenges facing small businesses, it repeatedly chooses its own expansion over results. In effect, government has become a huge silent partner in all businesses, often taking a majority of the profits and fo...
There is no greater country on Earth for entrepreneurship than America. In every category, from the high-tech world of Silicon Valley, where I live, to University R&D labs, to countless Main Street small business owners, Americans are taking risks, e...
The genomics revolution, proteomics, metabolomics, all of these 'omics' that sound so terrific on grants and on business plans. What we're doing is we are seizing control of our evolutionary future. I mean we're essentially using technology to just j...
I never considered the clothing business in college. But my father was a manufacturer of men's wear in the Northeast and wanted to investigate manufacturing in Asia. In 1972 he sent me to Japan, Taiwan, and Hong Kong for four months. I'm convinced it...
I don't think that writing talent has much to do with where one went to school, or the number of degrees on one's business card, but I do get a bit bristly at the implication that romance authors couldn't possibly be smart enough to get into an Ivy L...
Every breakthrough business idea begins with solving a common problem. The bigger the problem, the bigger the opportunity. I discovered a big one when I took apart an IBM PC. I made two interesting discoveries: The components were all manufactured by...
In my business, if I get too close to you and you die, it hurts me. And so you develop a natural inclination not to be close to the patient, so that if things don't work out ideally, you can still get up the next day and care for the next patient.
It's funny; it's a real balancing act. In TV, everybody's talking about authenticity. In order to make 'Dirty Jobs' authentic, I really can't be overly informed. The minute I am, I become a host... It's a very tricky business paying a tribute to work...
Don't solicit feedback on your product, idea or your business just for validation purposes. You want to tell the people who can help move your idea forward, but if you're just looking to your friend, co-worker, husband or wife for validation, be care...
If you look at the economics of Nokia, roughly half of the company, half of the business, half of how we think about the business is focused on those emerging markets and on those lower-priced devices. But, of course, people who are aspirational and ...
If you wait for customers to tell you that you need to do something, you're too late. Good business leaders should be half a step ahead of what customers want, i.e. they don't actually quite know they want it. That's what innovation's about. With Pla...
My four criteria: I don't want to work with people I don't like; I don't want to work in a business I either don't like or don't understand; I don't want to work for nothing unless I choose to, and I do a fair amount of that already; and I want to ha...
The important thing to remember with the Internet is that there are large companies that have an interest in controlling how information flows in it. They're very effective at lobbying Congress, and that pattern has locked down other communication me...
I spent a lot of years on the road, and what happens is you find out who your real friends are and you find out where your strengths and weaknesses lie in communication. I've had the same friends for 20 years now and I can count them on one hand.
My mindset is of the person who is still unsure whether they have enough money in their ATM to go to another bar. I lived that way when I was unemployed, when I was a snowboard instructor, and when I was at NYU. A lot of my personality is stuck in th...
The same stimuli in the world can be inducing very different experiences internally and it's probably based on a single change in a gene. What I am doing is pulling the gene forward and imaging and doing behavioural tests to understand what that diff...
This is how to avoid re-creating painful situations: Take the time to discover your real intention before you act. If it is to change someone or the world so that you will feel safe or better about yourself, don't act on it, because it is an intentio...
I think there's a mythology that if you want to change the world, you have to be sainted, like Mother Teresa or Nelson Mandela or Archbishop Desmond Tutu. Ordinary people with lives that go up and down and around in circles can still contribute to ch...
If you think about it, candidate Obama, Sen. Obama, was running on sort of long-run economic issues, like restoring prosperity to the middle class, dealing with the perennial problem of health care in the United States. He talked a lot about the budg...
Most people just half-watch TV. They watch TV while they are doing many other things in the environment of their home. So, what they are doing goes through their ears as much as through their eyes. In television, the narrative and characters are in t...
Worst part of being a writer: having to tell my toddler that I can't play with her because I'm working. Keep in mind that working consists of me at home with a laptop on my lap sitting on the couch. It doesn't look like working. I don't have a hammer...
