Neuroscientists talk a lot about brain circuits. In fact, the word 'circuit' is probably misleading. We do not know where most circuits begin and end. And unlike an electrical circuit, brain connections are heavily reciprocal and recursive, so that a...
I have a very high tolerance for gore and blood. I am, like, the perfect horror movie viewer because I do not get scared very easily. I can really stomach anything so, as a result, I have watched a lot of really disgusting stuff that I should probabl...
As supportive as my hometown is, in my high school, there are people who would probably walk up to me and punch me in the face. There's a select few that will never like me. They don't like what I stand for. They don't like somebody who stands for be...
When I'm talking about depression, I'm talking about the more severe forms of depression, and I think that conceptualising as a form of grief is probably not the most effective way of looking at it. I mean, at the end of the day, people suffer enormo...
The other day I was thinking - because I get a lot of headaches - I was wondering whether the head should be where it is. Because, at the end of the day, it's probably the heaviest part of your body, right? And yet it's at the top as opposed to, I do...
We have over an hour of footage with Ken Marino. Same with Kevin Smith. Because you never know, when you let people who are so talented at improv go, what you're going to get. You don't want to strangle them with your own words, because probably what...
I completely think of myself as sexual. Completely and utterly. Probably more so than I did when I was 30. I don't know why. I'm very comfortable with how I look. I'm absolutely committed to never having anything done to my face. I would never let an...
In the summer of 2012 - and we do as we do when we get together to brainstorm an idea - we were both probably eating grilled cheese and watching 'Oprah's Favorite Things,' so it will never end, and we both brought a few things to the table of what we...
As long as you don't tell your father that I seduced you, tied you to my bed and made love to you, then treated you like my personal sex slave, I'll probably make it through the meeting alive. Explaining dominant behavior isn't exactly easy. I'll be ...
Statistically, the probability of any one of us being here is so small that you'd think the mere fact of existing would keep us all in a contented dazzlement of surprise. We are alive against the stupendous odds of genetics, infinitely outnumbered by...
If you will have a person enslaved, the first thing you must do is convince yourself that the person is subhuman. The second thing you have to do is convince your allies so you'll have some help, and the third and probably unkindest cut of all is to ...
When I was on 'The Golden Girls,' we'd have eight scenes per show. And when 'Seinfeld' came along, they went to, like, 30 scenes a show, which was revolutionary. 'Arrested Development' has probably got 60 scenes per show. It just keeps emerging as th...
Birds have nests that seem to be inherent. I think there must be some kind of extended phenotype for humans. People probably have, inherently inside them the perfect psychological space that can be grown or developed at multiple levels. Maybe it's a ...
I have been a print reporter my whole career. It's all I ever wanted to be. I specialize in political profiles. I have probably profiled hundreds of people over the years, people in very powerful positions. People don't always like what I write, but ...
I probably made a few pictures I shouldn't have done, but I have four sons and I have to pay the rent. If you have a decision to make about whether or not you can buy groceries at the market or whether or not you're going to make a bad movie, you're ...
(there is) no other means of escaping from one's consciousness than to deny it, to look upon it as an organic disease of the terrestrial intelligence - a disease which we must endeavor to cure by an action which must appear to us an action of violent...
Let's cut to the chase, the sharia controversy. I don't think I, or my colleagues, predicted just how enormous the reaction would be. I failed to find the right words. I succeeded in confusing people. I've made mistakes - that's probably one of them.
My first favourite book was 'Are You My Mother?' A picture book about a lost bird. After that my favourites changed almost yearly. I loved everything by Roald Dahl, but my favourite was probably 'Charlie and the Chocolate Factory.' A librarian gave m...
I grew up pretty secular. I went to public school, and all the Jews that I knew, none of them were religious. While probably half of my friends were Jewish, they were all secular Jews. We went to Hebrew school, we knew we were Jewish, but it wasn't a...
The first film that I can remember seeing where, like, I just couldn't stop watching it - and it didn't necessarily make me want to be a director because I was so young, but it made me know that that's what I wanted to be doing - was 'Alien.' And I s...
Sometimes when you think you are done, it is just the edge of beginning. Probably that's why we decide we're done. It's getting too scary. We are touching down onto something real. It is beyond the point when you think you are done that often somethi...
