I'm choosy to a fault. You want to hold out for a project that means something. You're the one who's there working fifteen hours a day, and if you don't believe in it, it can feel a whole lot longer.
In the late 1970s, when I was a professor at Caltech, I pioneered four instruments for analyzing genes and proteins that revolutionized modern biology - and one of these, the automated DNA sequencer, enabled the Human Genome Project.
I have this vision of maybe going the way of Bill Kurtis and, I think, Tom Brokaw, to a certain extent - the ability to not be tied to the desk anymore, but to do projects that are meaningful to you.
People enjoy the interaction on the Internet, and the feeling of belonging to a group that does something interesting: that's how some software projects are born.
As I started to develop as a director, I wanted to do projects that were inherently more cinematic, where the freight was not so much in the dialogue, where it would be carried more by the camera.
I've always thought of the project as a sort of sexually driven digestive system, that it was a consumer and a producer of matter. And it is desire driven, rather than driven by hunger or anything like that.
Many people think that open source projects are sort of chaotic and and anarchistic. They think that developers randomly throw code at the code base and see what sticks.
Some of these sketches were done at the very beginning of the Pirates project, when I was trying to find a direction for myself. That was the early sixties... maybe 61 or 62.
One answer is that the town's elected officials thought that the project served a public purpose and that the various subsidies and favors were worth the price. But they may or may not have thought this.
For me, it was a lot of pressure to make another movie after 'Inglourious Basterds' because I didn't want to do something wrong. I wanted to have a beautiful project for another American movie.
I wasn't a cheerleader or the prom queen. I don't move through the world with a mirror in front of my face, and I've never been attracted to projects that had an emphasis on what I look like.
If you're going to immerse yourself in a project for three years, why not stake out a chunk of the world that is completely alien to you and go traveling?
I really like writing for specific projects. It's a whole different way of writing when you have certain guidelines and a theme you're writing to. It's very inspiring.
I definitely wouldn't shy away from doing another action based project, but I feel like my forte is more like playing real, ordinary people. I'm a girl's girl.
By the year 2040, the world's population is likely to increase by about 2 billion people, with also projected economic output will be up about 130 percent versus the year 2010.
It's always overwhelming when you get a nice response to something, because you really invest in these projects, and you can't help but really care what other people think.
I mean I have a project that I have been wanting to make for quite a while now; and basically, it's a story of my parents growing up in the Lower East Side.
I was with Ted Turner when he came to see Kofi Annan - the Secretary-General of the UN - to announce his decision to put $1 billion to the service of UN projects and programs.
Further, Japan is the second largest donor in Iraq after the United States, with over $5 billion dollars for humanitarian, infrastructure and reconstruction projects.
When you're facing an investor or the institutions or a distributor, it's you yourself with your own ideas and your own project.
Perhaps the most striking assault on the foundations of traditional liberties is a little-known case brought to the Supreme Court by the Obama administration, Holder v. Humanitarian Law Project.