Random mutations much more easily debilitate genes than improve them, and that this is true even of the helpful mutations. Let me emphasize, our experience with malaria’s effects on humans (arguably our most highly studied genetic system) shows tha...
There is talk of a new astrologer [Nicolaus Copernicus] who wants to prove that the earth moves and goes around instead of the sky, the sun, the moon, just as if somebody were moving in a carriage or ship might hold that he was sitting still and at r...
I love Israel, I go back all the time. I just love New York a little more. My workers are Arabs, my best friend is a black man from Alabama, my girlfriend's a Puerto Rican, and my landlord is a half-Jew bastard. You know what I did this morning? I re...
I believe that almost all our sadnesses are moments of tension that we find paralyzing because we no longer hear our surprised feelings living. Because we are alone with the alien thing that has entered into our self; because everything intimate and ...
If Gissing is less compassionately observant than Mrs Gaskell, less overtly polemical than Kingsley, still and would be sympathetically endorsed by either of them, or by their typical readers. Yet Gissing does introduce an important new element, and ...
This American system of ours', he shouted, 'call it Americanism, call it capitalism, call it what you like, gives to each and every one of us a great opportunity if only we seize it with both hands, and make the most of it'. A month later in New York...
There was just such a man when I was young—an Austrian who invented a new way of life and convinced himself that he was the chap to make it work. He tried to impose his reformation by the sword, and plunged the civilized world into misery and chaos...
There used to be a rubbish heap under the great tree in Dhoby Ghaut with a sarabat stall parked next to it. It was a low, sprawling rubbish heap made up of the usual things—refuse from dustbins, paper, old tins and slippers and leaves from the tree...
Sit down. Inhale. Exhale. The gun will wait. The lake will wait. The tall gall in the small seductive vial will wait will wait: will wait a week: will wait through April. You do not have to die this certain day. Death will abide, will pamper your pos...
Do not limit yourself to your own preconceptions of yourself, but throw yourself out onto a blank page that you haven't written on yet, and see what you find out about you, see what story unfolds, see what happens! I always do this, and sometimes it ...
When ladies as young, and good, and beautiful as you are," replied the girl steadily, "give away your hearts, love will carry you all lengths--even such as you, who have home, friends, other admireres, everything to fill them. When such as I, who hav...
Perceptive people like you wound more easily than others. But if we’re going to work on God’s side, we have to decide to open our hearts to the griefs and pain all around us. It’s not an easy decision. A dangerous one too. And a tiny narrow doo...
The world's a headmaster who works on your faults. I don't mean in a mystical or Jesus way. More how you'll keep tripping over a hidden step, over and over, till you finally understand: Watch out for that step! Everything that's wrong with us, if we'...
Were we to confront our creaturehood squarely, how would we propose to educate? The answer, I think is implied in the root of the word education, educe, which means "to draw out." What needs to be drawn out is our affinity for life. That affinity nee...
The journey through another world, beyond bad dreams beyond the memories of a murdered generation, cartographed in captivity by bare survivors makes sacristans of us all. The old ones go our bail, we oblate preachers of our tribes. Be careful, they s...
Science accepts only facts that are available only through our brain and sense organs. What would happen, if we had more complex brain design and more complicated sense organs? Only imagine more active and differently functioning neurons of our brain...
With heart at rest I climbed the citadel's Steep height, and saw the city as from a tower, Hospital, brothel, prison, and such hells, Where evil comes up softly like a flower. Thou knowest, O Satan, patron of my pain, Not for vain tears I went up at ...
Having been tenant long to a rich Lord, Not thriving, I resolved to be bold, And make a suit unto him, to afford A new small-rented lease, and cancell th’ old. In heaven at his manour I him sought: They told me there, that he was lately gone About ...
I still dream to quiver rich, And we still tremble poor. Over, under, Madam and Bitch, To each, her John Does floor. Grieved cliche to ban the kiss, And yet we all refuse. To add one name onto our lists, Of cants, and don'ts, and dudes. Unuttered sig...
Burke's admonition--"The effect of liberty to individuals is, that they may do what they please: We ought to see what it will please them to do, before we risk congratulations"--never seems to have occurred to Hayek. The Arnoldian ideal of the disint...
my phone beeped. I took it from my handbag and saw a text message from Dixie. It read: that man is sizzling HOT HOT HOT!!!! truth! I texted back. omg! his accent! his body! im in lurv i noticed! hes a bilf wtf??? boss id like 2 fuk! I snorted out lou...