Genes are effectively one-dimensional. If you write down the sequence of A, C, G and T, that's kind of what you need to know about that gene. But proteins are three-dimensional. They have to be because we are three-dimensional, and we're made of thos...
I made a lot mistakes that I'm grateful for, because I won't make them again and I won't let my artists make them, or I'll tell them, 'Don't do this.' A lot of them still make them anyway, but you can't be told things when you're doing your own thing...
The publication in 1859 of the Origin of Species by made a marked epoch in my own mental development, as it did in that of human thought generally. Its effect was to demolish a multitude of dogmatic barriers by a single stroke, and to arouse a spirit...
A little girl and her father were walking along in the evening. She was fascinated by the stars, and kept looking up at them, but made no comment until her father asked what she was thinking. She replied, "If the bottom side of heaven is so beautiful...
When I took part in European leaders summits, it was sometimes unpleasant for me to hear Romanian, Polish, Portuguese, and Italian friends speak English, although I admit that on an informal basis, first contacts can be made in this language. Neverth...
Like so many poor Ilokanos, my grandparents left their village, for it could no longer sustain them. The Ilocos is a narrow coastal plain where, so often, the mountain drops to the sea. Land hunger had always afflicted the Ilokanos and made them migr...
I wasn't trying to be a role model with 'The Dutchess,' but suddenly, seeing little girls in the audience with their moms made me think about what I do onstage a little bit more. I had to watch my mouth, because it can be filthy. It changed things fo...
When I did '1,2,3,4' on 'Sesame Street' they'd rewritten the song and made it about counting. At first, I balked. I was like, 'Counting to four? That's where we're going with this?' Then they sent me appearances by other people like James Blunt doing...
At morn we buried Melanippus; as the sun set the maiden Basilo died by her own hand, as she could not endure to lay her brother on the pyre and live; and the house beheld a two-fold woe, and all Cyrene bowed her head, to see the home of happy childre...
Good organization,” said Magnus. “I knew the man who founded it, back in the 1800s. Woolsey Scot. Respectable old werewolf family.” Alec made an ugly sound in the back of his throat. “Did you sleep with him, too?” Magnus’s cat eyes widene...
There was a stool there, and some fella kept asking me if I wanted to sit down. When I saw the stool sitting there, it gave me the idea. I'll just put the stool out there and I'll talk to Mr. Obama and ask him why he didn't keep all of the promises h...
When I was young, Tchaikovsky was ruined for me by conductors who made it slick and treacly. Hearing Valery Gergiev conduct Tchaikovsky has been a revelation - he brings out all its raw passion. And Gergiev with the super-virtuoso LSO - well, it's ju...
With acting, I started very young, and I'd performed for a lot of children in boarding schools, late at night after the dormitory lights were out. I'd have a flashlight, and I'd be Count Dracula, or Shakespeare, or Yogi Bear, and leap from bunk to bu...
You get to a point where you have to start planning, when you cross that line where you have enough value to get someone's movie made if you attach yourself to it, you have to be very thoughtful and have to plan. When you're starting out, you're will...
I never set out to do this; I never set out to say, 'Can I break this record?' Then all of a sudden, the preparations made for the celebration put pressure on me. I said, 'Okay, I have to get there.' After 2,130, there was sort of a realization it wa...
I'd like to think that, at the end of the day, you can look at the things that I made as a young person and the things I'll continue to make as I get older and they'll be consistently interesting and soulful things, and if you like them they'll be a ...
I always wanted to be a professional athlete, it just took me a while to realise it would be in racing. I played field hockey competitively for Ontario since I was 13, 14. Then I tried for the national side and made it. But it was so competitive. The...
Jesus kept it simple. The lesson wasn't complicated. 'I speak; you believe My word; your son will be fine.' We complicate what God has made simple by seeing the world through human eyes. We want to see in order to believe and presume that our limitat...
There is a reward structure in science that is very interesting: Our highest honors go to those who disprove the findings of the most revered among us. So Einstein is revered not just because he made so many fundamental contributions to science, but ...
Well, I can understand how you feel. You worked hard, studying for the spelling bee, and I suppose you feel you let everyone down, and you made a fool of yourself and everything. But did you notice something, Charlie Brown?" "What's that?" "The world...
I still have a stammer that I can control by not opening a sentence with a hard consonant, or by concentrating for a moment, breathing softly down. Growing up, the 'Our Father' was lovely, made for me, the 'Hail Mary' was gorgeous, and 'Glory Be to t...
