Rachel Hansen: PMS? Tom: What do you know about PMS? Rachel Hansen: More than you, Tom.
(500) Days of SummerKilgore: What the hell do you know about surfing, Major? You're from goddamned New Jersey!
Apocalypse NowJake: Oh my gosh! How do you know Mike Shiner? Lesley: We share a vagina.
Birdman: Or (The Unexpected Virtue of Ignorance)[before riding the bicycle] Etta Place: Do you know what you're doing? Butch Cassidy: Theoretically.
Butch Cassidy and the Sundance Kid