If you feel depressed for an hour, you've produced approximately eighteen billion new cells that have more receptors calling out for depressed-type peptides and fewer calling out for feel-good peptides.
It gets harder as times go by, because memory is the first casualty of manic depression. When I'm manic, all I remember is the moment. When I'm depressed, all I remember is the pain. The surrounding details are lost to me.
Examples one finds in the philosophical literature are somebody who's seen the trial of a child of theirs, where they're being proved guilty of some crime that would drive the parent into a depression, maybe a suicidal depression.
Human bodies are designed for regular physical activity. The sedentary nature of much of modern life probably plays a significant role in the epidemic incidence of depression today. Many studies show that depressed patients who stick to a regimen of ...
Judy's friend that she has known the longest has just broken up with her boyfriend and is depressed. Judy likes her more now that she is depressed and feels unmotivated in life. Judy feels unmotivated in life.
Some people think they're depressed and they go to the doctor and want pills. And you just think: 'You hate where you live, you've lost your job, your boyfriend has dumped you, could all this be why you're depressed?'
When public figures remain silent about depression, there is a cost to the rest of society. Silence contributes to the misperception that successful people do not get depressed, and it keeps the public from seeing that treatment allows many individua...
You say you're a writer but you're depressed. Not an excuse; write from there. Write some depressing sh*t. Believe me. You will have plenty of readers who can relate. Remember writers write.
A friend called the other day. 'How are you?' she said. The sun was shining, the sky a merciless blue. It was only eleven in the morning but I had been awake since three twenty. I was in bed because, as usual, I could think of nowhere else to go. I s...
Depression is a painfully slow, crashing death. Mania is the other extreme, a wild roller coaster run off its tracks, an eight ball of coke cut with speed. It's fun and it's frightening as hell. Some patients - bipolar type I - experience both extrem...
Nesse’s research focuses on the evolutionary origins of depression. Why does depression exist at all? If it’s stayed in our gene pool for so long, he argues, there must be some evolutionary benefit. Nesse believes that depression may be an adapti...
Depression is easy to wallow in and hard to fight against, but if you just give in to it completely it's a downward spiral. You skip going to class because you're feeling depressed, then you stay in the rest of the day because you've already missed o...
A great Tamil poet, given to decadence and debauchery, once said that the story of his life could serve as an example to the youth on how one should not live. Having lived, or rather, having sleepwalked for ten years through the desolate wastelands o...
We have an internal check and balance system. By design we are so filled with possibility, opportunity, with greatness that when we live small, within the bottom of our capability, we innately know we should be living greater than that, and it create...
When I was in high school, I used to have breakfast with my grandpa every morning. He instilled a lot of values in me: hard work, loyalty. He grew up during the Great Depression in Philly in poverty - he didn't have enough to eat as a kid. Sometimes ...
More of anything only makes us more of what we already are. If we are happy, it can bring more happiness. If we are depressed, it will make us more depressed.
I do not think we were afraid of death; life had become such an infinitely boring alternation between a period of stimulation which failed to stimulate and of depression which hardly even depressed.
Maybe I just didn’t want it to be Benny because he really loves her, and if I was wrong about that, it’d be depressing. Who wants to be depressed?” “Poets,” Eve decided. “You have to think they must.” “Okay, other than poets.
There is no point treating a depressed person as though she were just feeling sad, saying, 'There now, hang on, you'll get over it.' Sadness is more or less like a head cold- with patience, it passes. Depression is like cancer.
Sometimes I think depression should be called the coping illness. So many of us struggle on, not daring or knowing how to ask for help. More of us, terribly, go undiagnosed.
When you're in the middle of your depression, pay good attention to it, because, tended carefully, you never know where it might lead you.