In the frantic search for an elusive 'cure,' few researchers stand back and ask a very basic question: why does cancer exist? What is its place in the grand story of life?
I think there's always interest in how the other half live - I see myself as a down-to-earth Essex mum who just happens to be living this very glamorous life in Beverly Hills.
My father started with nothing and is a self-made man. No matter what I do with my life, I can never match his accomplishments.
I've never looked ahead very much in my life. I've never had any grand plan from the outset. I had no burning ambition to do what I do.
I always accessorise with jewellery. I am a bit of a magpie; I love sparkles, and so wearing jewellery makes me feel more exciting and confident, too!
I actually love shopping in vintage shops. What I do with the high street, I buy it, then keep it for a while and then wear it when everyone's not wearing it. So I do that: stock up, then keep it hidden!
I really do love social media. I've always been crazy about - even like, remember AOL chat rooms? I always loved message boards, and I was always interacting on the computer.
I love to learn, and Victoria's Secret has given me more opportunities than I ever thought possible. I like doing things that scare me - I've learned never to doubt myself.
I can play the flute. Music was my favourite A-level, and I used to love composing my and stylising my voice to sound like 90's singing sensation Tori Amos.
I love the sun, but we don't get on at all; it doesn't agree with my Celtic tones. I also like nothing better than putting on a big ski jacket and feeling the wind in my face.
I do like shopping high street, but I do consider the long-term value of a specific piece and, also, one day giving it up for somebody else to love and enjoy.
I love the physicality of my job and how my mind and body are most happy when I'm expressing and moving. My face was always secondary to body alignment and the dynamism of making a moment come alive.
Fashion is intoxicating, and it plays a part in all of our everyday lives. A lot of people use it as a form of escape, of realising a fantasy, and in some ways that becomes an unobtainable norm.
Conformism is a potent statement, and as much as we do talk about individuality in fashion, there's a sense that people are fearful of not conforming and not being part of action.
I think most of my career has been built on conviction and the personality to carry that image or stride confidently on the catwalk. That was my beginning and, hopefully, my legacy.
My perfect bag would be practical but also have the stylish element to it; it would be bold and colourful. I would actually be able to open and close it. That would be a first.
Taking it as a whole, Mexico is a grand city, and, as Cortes truly said, its situation is marvellous.
Basically, I didn't know anything about fashion. I was very nerdy; I went to Bryn Mawr and never even noticed models when I was 21.
No babies for me until I'm in my 30s! I'm focused on my career right now. I can't even take care of my dog.
I don't like to fly. What's it called when the plane shakes? Turbulence, takeoffs... I grab my chair, close my eyes, count to 30, breathe, and pray.
And I think it's a real challenge to be up there sometimes with only a keyboard if they don't have a grand piano... and to try to win people over that way. It's really hard.