Our goal is not to completely eradicate the infection - that would be very difficult - but to produce a vaccine that will prevent not infection but disease. I think this is more possible.
Freedom is indivisible. As soon as one starts to restrict it, one enters upon a decline on which it is difficult to stop.
It is difficult to describe paths of thought where there are already many paths laid down, and not fall into one of the grooves
Life is a cake and love is the icing on top of it. Without 'love', it becomes difficult to swallow 'life'...
It's difficult sometimes when you have somebody who is of a different culture trying to make light of something that is maybe not quite something that they understand.
I find having a column a very difficult form of journalism. I'm not a natural like Tom Friedman and Anna Quindlen.
Sometimes it's difficult to accept, to recognise one's own mistakes, but one must do it. I was guilty of overconfidence and arrogance, and I was punished for that.
Anything difficult you do, anything thought to be impossible you achieved is always a great inspiration for the world!
It is difficult to love someone who loves you, but easy to hate someone who loves you, and love someone who hates you.
You have to write the book that wants to be written. And if the book will be too difficult for grown-ups, then you write it for children.
You have to write the book that wants to be written. And if it's too difficult for grown-ups, you write it for children.
Without effective protection of the citizens' right to property, it will be difficult to attract and accumulate valuable capital.
The ability to suspend reality and go into a make-believe world can be really, really difficult if there's something really big going on.
I can inhabit any character in a way that is difficult to do successfully in a contemporary novel.
It is seldom very hard to do one's duty when one knows what it is, but it is often exceedingly difficult to find this out.
I'm controlling, and I want everything orderly, and I need lists. My mind goes a mile a minute. I'm difficult on every single level.
For everything in life there is always a beginning and an end. This is the tough part the most difficult thing when you see that it’s coming: The end.
Software is like entropy. It is difficult to grasp, weighs nothing, and obeys the second law of thermodynamics; i.e. it always increases.
I embraced, I think, the process of becoming No. 1 of the world, which was long and difficult, but it's sweeter in the end.
Boys in bands are more difficult to deal with than one-year-old babies. I've been one of them, and I am one of them, but it is the truth.
It is easy to love but difficult to forget, so love every moment to create an enormous unforgettable memory.