Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Moreover, in order to understand any man one must be deliberate and careful to avoid forming prejudices and mistaken ideas, which are very difficult to correct and get over afterwards.
We find ourselves in a difficult situation in Europe. There's a crisis, weak growth, unemployment... my duty is to ensure that by the end of my mandate France is in a better state than it was at the beginning.
It's difficult to say what attracts one person to another. It's always a combination, isn't it? I've always found people interesting because of the way they think, and a sense of humour is irresistible.
It is simply the view, and a view I think shared by most members of the party, that it is very difficult to have a leader that does not command the support of the parliamentary party.
It's really not that difficult to be happy. You just have to be grateful and especially appreciate what you do have now. The rest will come, my dear.
It is difficult to talk about fashion in the abstract, without a human body before my eyes, without drawings, without a choice of fabric - without a practical or visual reality.
The tradition and style of the 'New York Times' make it very difficult to have objective coverage of China. If we could purchase it, its tone might turn around.
If we only wanted to be happy, it would be easy; but we want to be happier than other people, and that is almost always difficult, since we think them happier than they are.
I know it can be difficult for parents, but I really do believe that kids need to play the predominant role in the choices that go into their own space.
Being a typical teenager isn't easy. When you have autism, it can be extra difficult. We need more public awareness about these hurdles as well as compassion towards these young people.
The provocation with Holmes is the fact that he's described by Doyle as a man without a heart - all brain... and that's very difficult to play, or even indicate.
People have said that my films are very difficult to watch, that they're experiences you are put through rather than ones you enjoy, and it's true.
I still find it absurdly difficult to concentrate on a novel if there's a phone or computer to hand; I have taken to locking them outside the room like noisy pets.
Often I feel that projects overwhelm us when we look at how many hours are involved until completion. But just getting started is usually not that difficult.
You learn emotional experiences as much as you learn cognitive experiences, except that they are more unconscious. Sometimes one represses the cognitive component of it, but it's often more difficult to repress the emotional component.
As a guitar player, you can gravitate to the blues because you can play it easily. It's not a style that's difficult to pick up. It's purely emotive and dead easy to get a start with.
Elvis is not so difficult as Johnny Cash because his voice is so distinctive. If you try to copy Johnny Cash, it's just going to sound dumb.
I have to tell you, TV is an incredibly difficult medium. The most challenging show to do is the hour long dramedy. It's a very tricky format.
What is most difficult is when the large part of me that is a narcissist grows weary and is overtaken by the self-loathing part that always lurks in the shadows waiting for an opportunity to shine.
Repression in the human psyche is tightly bundled. When it has been pulled out of the sprung package so often it is perhaps difficult to push it back in the box.
