TP53 seems to encode the greater good, like a suicide pill in the mouth of a soldier that dissolves only when it detects evidence that he is about to mutiny.
I am somewhat exhausted; I wonder how a battery feels when it pours electricity into a non-conductor?
It was amusing to me to see how the detective's overbearing manner had changed suddenly to that of a child asking questions of its teacher.
I started to think about the abyss that separates the poet from the reader and the next thing I knew I was deeply depressed.
People aren't always who they seem, Detective. Am I anything like you thought?" "No," I admitted. You're a million times better than I could have imagined.
I remembered reading in a hard-boiled detective novel that if you drink in the same place two nights in a row, the bartender and waiters will remember your face.
People who believe in buried gods,’ said Louis. ‘Do you believe in buried gods, Detective Walsh?’ ‘I’m Episcopalian. I believe in everything.
They say that genius is an infinite capacity for taking pains," he remarked with a smile. "It's a very bad definition, but it does apply to detective work.
We women have intuition," Barby said loftily. "I wouldn't expect you to understand. I can't imagine why there aren't more women detectives.
The perfectly measured burr of a dispassionate detective had suddenly changed into the explosive boom of a take-no-shit street cop. Suffice it to say, I froze.
For the finale, I thought the audience deserved to get a close point of view on the monster, and to recognize him the way you recognize the heroes of 'True Detective.'
In the summer of 2010, I was working on a version of 'True Detective' that I was thinking might be my next novel, and it was told in these two first-person voices; Cohle and Hart's voices.
When I was young, I knew William Burroughs really well. And William's secret desire, which he never quite did, was to write a straightforward detective novel.
I think every writer of detective fiction writing today has been influenced by Mr. Parker. I'm of a generation that followed Robert Parker, and it was impossible to read the genre and not be influenced by him.
I'd like people to know that you can head off kidney disease, maybe prevent a transplant or stop the disease from progressing after detection by doing a simple urine test in the doctor's office.
I remember when I was 12, talking with my friends about what we wanted to do with our lives, astronauts, forensic detectives, all these different jobs. And the only thing I could think was an actor.
As a kid, I always wanted to be lots of things. I was a Walter Mitty type. I wanted to be in the French Foreign Legion, a detective, a doctor, a test pilot with a scarf, a fisherman who hauled in a tremendous marlin after a 12-hour fight.
When I was growing up, my stepmother's sister was the chief detective in one of the adjoining towns, so she piqued my interest in crime.
'The Big Sleep' would have been a more effective study of nightmarish existence had the detective been more complicated and had more curiosity been shown about his sweetheart's relation to the crime.
The third group is focused on counterintelligence and security. I think the reason for that is fairly evident, in terms of vulnerabilities of the department and the harm that can come to it by failing to detect when we have, in fact, been harmed.
I chose 'No. 1 Ladies' Detective,' or I'll say it chose me, and it was an absolute blessing, for the experience of being in Africa for seven months and learning so many different things, from languages to foods to greetings. On so many levels, it was...
