We often plough so much energy into the big picture, we forget the pixels.
Most practising scientists focus on 'bite-sized' problems that are timely and tractable. The occupational risk is then to lose sight of the big picture.
There are many people who can do big things, but there are very few people who will do the small things.
Cutting one side of your head for a few months is not a big deal compared with what other people have to deal with in the world. Plus, hair grows back.
I can't imagine having a conversation about 'Celebrity Big Brother' in Cambridge, Massachusetts.
I grew up in a courtroom kind of like the one you saw in 'To Kill a Mockingbird' - big, big courtroom, sometimes it didn't even have air conditioning.
It’s important to look at the big picture of life, as long as it’s not through a small screen
The truth for me is that I've been doing independent film since the get-go, so that's a big passion of mine, but the big ones are really fun, too. I like my world to be eclectic.
I know that I've got big ears and a big forehead and that my hair sticks up. But I'm happy with myself. I'm not necessarily trying to win a beauty pageant here.
Literally, there is a lot of talk about sparks in the Kabbalah. It talks about when God created the world initially, there was an explosion that happened like a Big Bang but based on vessels and light.
Probably because I'm from a middle class family, I have that nature in me that I don't get too excited with big things.
My most memorable food challenge was probably the Big Texan in Amarillo. All the big executives called me because it was such an iconic challenge, and a victory in that would be a legitimizing device for myself as much as for the show.
I came from a big family - two brothers and two sisters. So, there were always a ton of boys around and a ton of girls around. So, I grew up comfortable with both sexes.
When you worked in a studio it was the studio system that you kind of missed because it was a big, big family. I mean MGM had 5,000 people working a day there. You miss it.
Of course, my family has been a big reason for me to come back, especially my son who loves the game of hockey - he was a big reason for me coming back.
We don't have nannies and all that, we look after our own kids. It's just what you do. If you want a big family that's just what you do, isn't it?
When business became big business - conglomerates employing hundreds and even thousands of people - companies divided themselves into still smaller units.
People who don't take risks generally make about two big mistakes a year. People who do take risks generally make about two big mistakes a year.
I am always naturally drawn to heroines that have human flaws because I enjoy people that have lived their life with courage and make big successes and big failures.
I don't get rattled about the big things. I get rattled when I have to pick up my laundry, get gas in the car, pick up a script.
Gene Krupa was my big hero, and I used to play on my mother's flour cans and sugar cans with the kitchen knives, listening to the big bands on my dad's records. Gene Krupa and Harry James.