Clarice Starling: [to Hannibal Lecter] Your anagrams are showing, Doctor. Louis Friend? Iron sulfide, also known as fool's gold.
Hannibal Lecter: Closer, please. Clo-ser...
Clarice Starling: I graduated from UVa, Captain; it's not exactly a charm school.
Jame "Buffalo Bill" Gumb: YOU DON'T KNOW WHAT PAIN IS!
[referring to Clarice's deal] Dr. Frederick Chilton: You still think you're going to walk on some beach and see the birdies? I don't think so. I called Senator Ruth Martin. She never heard of any deal with you. They scammed you, Hannibal.
Roden: [Upon learning where the Death's-Head Moth came from] You mean this is like a clue from a real murder case? Cool! Pilcher: [to Clarice] Just ignore him, he's not a PhD.
Hannibal Lecter: Advancement, of course. Listen carefully. Look deep within yourself, Clarice Starling. Go seek out Miss Mofet, an old patient of mine. M-o-f-e-t. Go now, I don't think Miggs could manage again quite so soon, even though he is crazy. ...
Clarice Starling: Catherine Martin? Catherine Martin: Yes? Clarice Starling: FBI! You're safe! Catherine Martin: Safe? Shit! Get me outta here! Clarice Starling: You're all right, Catherine. Now, where is he? Catherine Martin: How the fuck should I k...
Pilcher: What do you do when you're not detecting, Agent Starling? Clarice Starling: I try to be a student, Dr. Pilcher. Pilcher: Ever go out for cheeseburgers and beer? The amusing house wine? Clarice Starling: Are you hitting on me, doctor? Pilcher...
Jack Crawford: Look at it, Starling. Tell me what you see.
Clarice Starling: But I thought the "yourself" reference was too hokey for Lecter, so I figured he's from Baltimore, and I looked in the phone book, and there's a "Your Self Storage" facility, right outside of downtown Baltimore, sir.
Roden: Sphingid ceratonia, maybe. [cuts open cocoon] Roden: Agent Starling, meet Mr. Acherontia styx. Pilcher: Weird. Roden: Better known to his friends as the Death's-head moth.
Hannibal Lecter: There are three major centers for transsexual surgery - Johns Hopkins, University of Minnesota, and Columbus Medical Center.
Boyle: [greeting Lecter in Memphis] Welcome to Memphis Dr. Lecter, I'm Lieutenant Boyle, this is Sergeant Patrick. Now we'll treat you as good as you treat us, you be a gentleman and you'll get three hots and a cot.
Miggs: I bit my wrist... LOOK AT THE BLOOD!
Dr. Frederick Chilton: What you are doing, Miss Starling is coming into my hospital to conduct an interview, and refusing to share information with me, for the third time. Clarice Starling: Sir, I told you, this is just a routine follow-up on the Ras...
Murray: [assessing the mutilated Sergeant Pembry] He's alive. Sergeant Tate, he's alive ! Sergeant Tate: Get a hold of him more and feel his hand son, talk to him. Murray: What do I say? Sergeant Tate: It's Jim Pembry now talk to him dammit!
Dr. Frederick Chilton: Crawford is very clever, isn't he, using you? Clarice Starling: What do you mean, sir? Dr. Frederick Chilton: A pretty young woman to turn him on. I don't believe Lecter's even seen a woman in eight years. And oh, are you ever ...