Quote from : The Black Hole War: My Battle with Stephen Hawking to Make the World Safe for Quantum Mechanics Book

There is a philosophy that says that if something is unobservable -- unobservable in principle -- it is not part of science. If there is no way to falsify or confirm a hypothesis, it belongs to the realm of metaphysical speculation, together with astrology and spiritualism. By that standard, most of the universe has no scientific reality -- it's just a figment of our imaginations.