Quote from : Self-Knowledge for Spiritual Awakening Book

Low states are a like a poison to the psyche. Millions of people throughout the world take tranquillizers each day to combat depression, but this does not tackle its root cause, which is found in the basic state of the internal energies of the psyche. Basically the energy of the psyche needs to change, from low states to spiritual ones. It requires inner observation, the destruction of the egos, and alchemical transformation.